Tubal Factor Infertility - by Dr Ankita Kaushal


Tubal Factor Infertility :
Why are fallopian tubes important?
Fallopian tubes are hollow muscular tubes, inside they are lined by hair-like bristles, they originate from the uterine cavity and end on top of ovaries. There are 2 fallopian tubes one on each side. The ovarian end has finger-like structures that help to suck in the egg in the tube after ovulation. The sperms swim from the vaginal cavity into the uterine cavity to the tubes. The egg is fertilized by the sperms in the tubes. This is where embryo forms and starts to develop further. After few days of development in the tubes, the embryo is shifted to the uterine cavity where it implants after which you are pregnant.
In case of any kind of damage to the fallopian tubes, the sperms will not reach the egg for fertilization, the embryo might not form, the embryo might not survive in damaged tubes.
For all of the above to happen and pregnancy to occur, PATENT AND FUNCTIONAL FALLOPIAN TUBES ARE MOST IMPORTANT.




What damage can happen to the tubes?
1.       One or both tubes can be blocked.
Tubes can be blocked at the point of origin from the uterus (proximal block or cornual block) in which case sperms will not be able to reach the egg and fertilization will not happen.
Tubes can be blocked at the fimbrial end (near the ovaries). In this case, fluid can get accumulated in the tubes, which might drain in the uterine cavity and hamper implantation of the embryo (in case of IVF/ICSI).
2.       Tubal scarring due to previous surgeries (ruptured appendix, ruptured ectopic pregnancy, ovarian torsion, ruptured ovarian cyst, endometriosis.)
3.       Disturbed tubal anatomy ( adhesions due to pelvic infections , endometriosis, previous surgeries, pelvic tuberculosis).
4.       Kinking of the tubes due to adhesions.
What are the causes of Tubal damage? :
1.       Infections : pelvic infections; sexually transmitted diseases such as chlamydia, gonorrhoea; pelvic tuberculosis.
2.       Endometriosis .
3.       Ruptured Ectopic pregnancy. ( affected tube is removed)
4.       Previous surgeries for ruptured appendix, ovarian cyst, endometriosis, ectopic pregnancy.
5.       History of Tubal ligation

How to diagnose tubal problem ?
Tubes are usually checked only when a couple is evaluated for infertility. It is commonly found in younger age groups.
1.       HYSTEROSALPINGOGRAM: a dye is passed through your uterus, if tubes are open, passes through the tubes and leaks into the pelvis. X RAY films are taken at 0, 5 and 10 minutes to record presence/ absence of dye in the tubes and leaking into the pelvis. Done on OPD basis, no anesthesia required.
2.       SONOSALPINGOGRAPHY: sterile normal saline is passed through the uterine cavity with the help of a flexible catheter. On sonography presence of saline (water) is seen below the uterus, suggesting the either one or both tubes are open and that is how saline leaked into the pelvic cavity. It is an OPD procedure, no anesthesia required.
3.       HIGH CONTRAST SONOSALPINGOGRAPHY: same as sonosalpingography, but in place of normal saline, contrast is passed which is visible on sonography. It is an opd procedure, no anesthesia required.
4.       LAPAROSCOPY AND CHROMOPERTUBATION: a laparoscope is inserted in the lower part of the tummy. Methylene blue dye Is passed into the uterus and is documented under direct vision if tubes are open ( dye flows out) or blocked ( dye does not flow out). This is gold standard for diagnosis of blocked tubes. It requires anestheia and hospital admission.
What is other diagnosis , If tubes are not blocked ?
1.       Tubal muscle spasm ( cornual , fimbrial) : Sometimes due to mild pelvic infections or any other reasons, the two open points of the tubes ( uterine end and ovarian end) can go into spasm. This can give a blocked tube like of picture on HSG/SSG/HYCOSY. Only on laprascopic evaluation, if the dye id pushed forcefully, it might relieve the muscle spasm and tubes will be patent and functional.
2.       Thin adhesions : Due to some other pathology or previous surgery, thin flimsy adhesions form that might cause kinking of tubes, giving an impression of blocked tubes. On laprascopic evaluation, once the adhesions are removed, tubes become patent and functional.
How to treat blocked tubes?
1.       If tubes are normal in structure and are blocked due to other problems ( tubal muscle spasm, thin adhesions) once the correction is done, tubal function is restored.
2.       If tubes are blocked but there are no signs of any other pathology, tubal recannulation can be done to relieve muscle spasm. This will restore functional capacity of the tubes. Tubes can get blocked after this also. This also might increase chances of Ectopic pregnancy.
3.       If the tubal pathology is severe ( bilateral block, tuberculosis, hydrosalpinx, endometriosis), ASSISTED REPRODUCTIVE TECHNIQUES (IVF/ICSI) give better chances of achieving pregnancy.
4.       In case of hydrosalpinx ( fluid filled in tubes) or pyosalpinx (pus filled in tubes), it might drain into the uterine cavity decreasing the chances of implantation of embryo. In such situations, removal of affected tube/tubes or clipping of tube/tubes should be done, to increase chances of pregnancy following embryo transfer.

For more information contact 
9136875667/ 02227714482.

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